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Tapentadol, a mu-opioid receptor agonist, binds to specific sites in the brain to reduce the sense of pain. Its dual mode of action, as both a pure mu-opioid receptor agonist and an inhibitor of the reuptake of the neurotransmitter norepinephrine, provides enhanced analgesia with fewer side effects compared to other opioids. This results in rapid pain alleviation, often within 30 minutes of ingestion, with effects lasting for 4-6 hours.
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